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Dodgers vs. Phillies Major League Baseball Prediction, Odds & Expert Picks Today

Mike Spector

Last Updated: April 5, 2025 9:54 AM EDT • 2 min 50 sec read.

Dodgers vs. Phillies Major League Baseball Prediction & Picks: Best MLB Odds for April 5
Pictured: Philadelphia Phillies second base Bryson Stott tags out Los Angeles Dodgers designated hitter Shohei Ohtani. Photo by Bill Streicher via Imagn Images.

The Los Angeles Dodgers (8-1) look to bounce back from their first loss of the season when they face the Philadelphia Phillies (6-1) in the second game of a three-game set. First pitch from Citizens Bank Park in Philadelphia is set for 4:05 p.m. ET (FS1).

Los Angeles was the first defending champion to start 8-0, but suffered its first loss of the season on Friday. Our Dodgers vs. Phillies Major League Baseball prediction expects Philadelphia to continue its unbeaten home record in a mild upset as -105 moneyline underdogs.

💰 Best Dodgers vs. Phillies predictions for today

Here are my best Dodgers vs. Phillies predictions for today's MLB matchup, with my pick confidence based on a 1-to-5-star scale. Be sure to check out the rest of our MLB picks, along with our guide on how to bet on the MLB.     

🔢 Dodgers vs. Phillies odds & betting lines

Here are the latest Dodgers vs. Phillies odds and betting lines from our best live betting sites.

📊 Who will win today's matchup?

As of Saturday morning, the Dodgers are favored to beat the Phillies in today's MLB matchup at 4:05 p.m. ET from Citizens Bank Park in Philadelphia. Philadelphia is a perfect 4-0 at home, so I’m predicting the Phillies will beat the Dodgers as -105 moneyline underdogs.

🎯 Dodgers vs. Phillies score prediction: Phillies 5, Dodgers 4

Not taking anything away from the Dodgers’ historic 8-0 start, but this impressive stretch has not come without flaws. Los Angeles has trailed in seven of its first nine games, and not having Freddie Freeman active for the seventh time this season will eventually catch up with the Dodgers.

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Through the first two starts of his MLB career, prized prospect Roki Sasaki has walked an alarming 34.6% of batters. 

And though his ground ball rate now sits at 41.7%, just one-third of his outs in his debut were ground ball outs. That is a dangerous way to approach a home run-happy Phillies lineup in a hitters park like Citizens Bank.

I predict Philadelphia will beat Los Angeles by a final score of Phillies 5, Dodgers 4. 

Best bet: Phillies ML (-105 via BetMGM)

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1️⃣ First-inning prediction: YRFI

1-2 sentences of analysis

🚑 Dodgers vs. Phillies injuries

Sasaki has allowed two first-inning runs in his first two games, while Phillies righty Aaron Nola has allowed 35 career home runs in the first inning, his second-most in any inning. If Sasaki’s control issues start early, Philadelphia is ripe to capitalize. 

📺 How to watch Dodgers vs. Phillies

⚔️ Matchup: Dodgers vs. Phillies
📅 Date: Saturday, April 5
🕗 Time: 4:05 p.m. ET
📍 Location: Citizens Bank Park (Philadelphia)
📺 TV: FS1
💻 Streaming: MLB.TV/YouTube TV

❓ Dodgers vs. Phillies FAQs

Who is favored to win Dodgers vs. Phillies?

The Dodgers are trading as -115 moneyline favorites at our best sporting betting sites, which gives them a 53.49% implied win probability.

What are the odds for Dodgers vs. Phillies?

The Dodgers are as high as +160 to lay the -1.5 runs with the runline, while Philadelphia’s best odds are -175 at BetMGM at +1.5. Our top sports betting apps are split between a total of 8.5 and 9 (+100/-120) runs. 

What time is Dodgers vs. Phillies tonight?

First pitch from Citizens Bank Park is scheduled for 4:05 p.m. ET.

How to watch Dodgers vs. Phillies

The Dodgers vs. Phillies Major League Baseball matchup airs on FS1.

🏆 MLB betting odds pages

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🧢 Best MLB betting sites

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Written By:
Mike Spector
Mike started in the sports writing industry in July 2019, and gained a lot of followers in his first year after finishing with the No. 2 overall record in an annual NFL betting competition, which made picks against the spread, and from an Over/Under and moneyline perspective. Mike is an avid fan of the NFL, MLB, tennis, and all college sports. In his opinion, March Madness is the best sporting event there is, and he's especially euphoric starting with conference tournament time in college basketball. Mike's a big advocate of "fading the public" and making plays that are contrarian, constantly citing that "there are reasons why they have those big shiny buildings in Las Vegas." When making wagers, Mike always scours the best odds at all of the major sports betting sites, where he mostly sifts through DraftKings, FanDuel, BetMGM, and bet365. He's tried several others and is of the firm belief that bettors should not just stick to one sportsbook, as there is always likely better value to be had with the same wager. In addition, while Mike received his undergraduate degree from Villanova University, he has no issue betting against the Wildcats when it comes to college basketball wagering, and suggests other bettors should always put their “head” before their “hearts.”