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Grizzlies vs. Thunder Prediction, Odds & Expert Picks Tonight: Game 2 NBA Playoff Preview

Shane Jackson

Last Updated: April 22, 2025 5:06 PM EDT • 3 min 17 sec read.

Grizzlies vs. Thunder prediction
Pictured: Oklahoma City Thunder guard Shai Gilgeous-Alexander handles the ball against the Houston Rockets during the third quarter. Photo by Erik Williams / Imagn.

Two days after a 51-point route in Game 1, the Oklahoma City Thunder will look to take a convincing 2-0 series lead when they host the Memphis Grizzlies tonight. Tipoff from Paycom Center in Oklahoma City is at 7:30 p.m. ET (TNT).

The Thunder are 15-point betting favorites for Game 2 this evening, which is two points more than the closing spread for the opener. Our Grizzlies vs. Thunder prediction and expert picks anticipate another lopsided affair as part of our Round 1 NBA picks.

📡 How to watch Grizzlies vs. Thunder live tonight (Game 2)

📅 Tuesday, April 22
🕗 7:30 p.m. ET
📍 Paycom Center (Oklahoma City)
📺 TNT | 🛜 Max

📈Grizzlies vs. Thunder betting insights

Here are some betting insights in the hours before tipoff for the Grizzlies vs. Thunder matchup via BetMGM:

  • The Thunder are drawing significantly more action on the spread despite dealing with a predictably larger number after trouncing the Grizzlies in Game 1, with 62% of the attention so far going toward them
  • The action is closer when we look at the total, with 56% going toward the Over on 228.5 points
  • The spread for Game 2 has dropped a little since the opening number of -16 in favor of Oklahoma City, and it now commonly rests at -14.5 through our best NBA betting sites

📊 Best Grizzlies vs. Thunder odds, records, stats & trends - Tuesday, April 22

📈 Check out our Grizzlies vs. Thunder matchup info for full team stats and betting line history.

💡 Grizzlies vs. Thunder predictions, expert picks & best bets: Game 2

✅ Against the spread pick: Thunder -14.5 (-110 via Caesars) ⭐⭐⭐
✅ Moneyline pick: Thunder (-1000 via BetRivers) ⭐⭐⭐⭐
✅ Over/Under pick: Under 229.5 (-110 via FanDuel) ⭐⭐

Grizzlies vs. Thunder Game 2 Prediction, Odds & Expert Picks: NBA Playoffs, April 22
Pictured: Oklahoma City Thunder guard Shai Gilgeous-Alexander gestures after a play against the Memphis Grizzlies during the first quarter at Paycom Center. Photo by Alonzo Adams via Imagn Images.

🎯 Grizzlies vs. Thunder Game 2 prediction

  • Thunder 121, Grizzlies 101

📰 Grizzlies vs. Thunder Game 2 preview

To fully understand how lopsided this series is, look at Shai Gilgeous-Alexander’s stat line from Sunday. The likely MVP finished with 15 points on 4-of-13 shooting, recording five assists and three rebounds. The league’s scoring champion was limited to his lowest offensive output of the year, yet his team still won by 51.

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Of course, the Grizzlies faced a challenging travel situation after playing Friday’s play-in game. However, it’s hard to envision them containing SGA for another game in this series.

The Thunder won’t win another game by 50-plus points, but I wouldn’t be surprised to see a few more blowouts by the end of the week.

✅ Best bet: Thunder -14.5 (-110 via Caesars)

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⛹️ Best NBA player prop bet for Grizzlies vs. Thunder: Game 2

🔎 Our NEW NBA player prop odds tool can help you find the best NBA odds across legal sportsbooks in your area!

🔥 Shai Gilgeous-Alexander Over 31.5 points ⭐⭐⭐⭐

I’ll buy any dip on SGA’s scoring prop, especially in this matchup. The Grizzlies play at an uptempo pace, providing more opportunities for the Thunder and their MVP guard to score.

Before Sunday’s performance, Gilgeous-Alexander had cleared his scoring prop in four straight games against Memphis. He averaged 36.25 points per game in four regular-season meetings against the Grizzlies.

This line is as high as 32.5 in the market, suggesting the value on FanDuel’s total for SGA.

💰 Best odds: -114 via FanDuel

Same Game Parlays
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🚀 Best same-game parlay (SGP) for Grizzlies vs. Thunder: Game 2

🧪 Want to make your own SGP? Check out our NEW parlay calculator to get the best odds for any same-game parlay.

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📈 Live Grizzlies vs. Thunder odds & Game 2 betting lines

Latest Grizzlies vs. Thunder odds from our best sports betting sites.

🪧 Grizzlies vs. Thunder Game 2 opening odds

Opening odds via BetMGM.

  • Spread: Grizzlies +15.5 (-115) | Thunder -15.5 (-105)
  • Moneyline: Grizzlies +775 | Thunder -1429
  • Over/Under: Over 228.5 (-115) | Under 228.5 (-105)

🚑 Grizzlies vs. Thunder injury report & lineup notes: Game 2

📋 Follow the official NBA injury report for more injury news.

🔮 Expert Grizzlies vs. Thunder picks

💵 Best NBA betting sites

Ready to bet on the NBA playoffs? Check out the best NBA betting sites and best sportsbook promos for today's games:

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Written By:
Shane Jackson
Shane Jackson has been writing for Sportsbook Review since 2022, though his passion for sports, writing, and betting runs much longer than that. He graduated from the University of Kansas with a journalism degree in 2017 and has been covering sports ever since, working for MLB.com, Manhattan Mercury, Lawrence Journal-World, WynnBET, Bet Chicago Sports, BetNOLA, and BetMGM. Jackson cares about creating quality sports betting content above all else. He uses a mixture of models, information, film, analysis, and a top-down approach to locate every best bet shared for SBR. He never gives out a pick that he wouldn’t be willing to spend his own money on. Jackson is focused on finding +EV bets on a daily basis for a variety of sports such as NCAAF, NCAAB, NFL, NBA, WNBA, and MLB. He usually bets on props but is willing to wager on a spread or total when there is an edge. Don’t ask him how many bets he has placed on a typical college football Saturday. Jackson doesn’t care if you follow him on social media, but his Twitter account has info on how you can follow his bets through multiple third-party platforms. He just wants you to read all the great work from the SBR team.