Barcelona vs. Borussia Dortmund Prediction, Expert Pick & Odds: Champions League Quarterfinal
Barcelona and Borussia Dortmund square off in a Champions League quarterfinal on Wednesday. While making it to this point in the competition is a feather in most teams' caps, this match pits one of the Champions League odds front-runners against the side at the bottom of the list. Barcelona's irrepressible form has them heavily favored over a Borussia Dortmund side that has struggled mightily in the Bundesliga.
Our Barcelona vs. Borussia Dortmund prediction piggybacks on that narrative, expecting the prohibitive home betting favorites across our soccer betting sites to live up to the hype while featuring a player familiar with scoring against the German side.
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🔮 Barcelona vs. Borussia Dortmund predictions
Champions League picks are based on the odds at our best soccer betting sites. Pick confidence is based on a 1-to-5-star scale.
🚨 Barcelona vs. Borussia Dortmund best pick: Barcelona and Over 2.5 goals (-135 via BetMGM) ⭐⭐⭐⭐
🚨 Barcelona vs. Borussia Dortmund player prop: Robert Lewandowski anytime goal (-130 via DraftKings) ⭐⭐⭐⭐
🏆 Who will win Barcelona vs. Borussia Dortmund?
🎯 Barcelona and Over 2.5 goals ⭐⭐⭐⭐
Best odds: -135 via BetMGM | Implied win probability: 57.45%
Despite their domestic struggles this season - in which they are in eighth place in the Bundesliga - Borussia Dortmund almost always show their best in the Champions League. They're a squad built for Europe's elite club competition, knowing how to use their pedigree and experience to elicit optimal results.
Dortmund surprised most onlookers by making it to last season's Champions League final. They were overlooked for much of that campaign but found a way to get past Atletico Madrid and PSG en route to the showcase match against Real Madrid.
This year, however, will be different.
Barcelona - who are unbeaten in 22 games, 18 of which were wins - are the best side on the continent. They haven't lost a game in 2025 and are in contention to secure a quadruple. Not only are they undefeated in 2025, but manager Hansi Flick has an unblemished record against Dortmund, winning seven straight.
Dortmund have only won three of 20 matches in Spain, the final nail in their prospective coffin.
Barcelona won 3-2 away to Dortmund during the group phase, and I expect a similar result at home. Our Champions League AI predictions for the quarterfinals predicted a 3-1 Barcelona win.
That scoreline fits the bill for this match. However, due to Dortmund's uncanny ability to play out of their skin on European nights, I predict a 2-1 Barcelona victory.
🥅 Best Barcelona vs. Borussia Dortmund pick
⚽ Robert Lewandowski anytime goal ⭐⭐⭐⭐
Best odds: -130 via DraftKings | Implied win probability: 56.52%
Look at those odds for Lewandowski to score his 104th Champions League goal. The 56.52% implied probability at DraftKings makes sense when you consider that Lewandowski scored 27 goals in as many matches against Dortmund since leaving the club 11 years ago. When you look at that goal-per-game clip, the -130 odds feel like a bargain.
Lewandowski has the fourth-most goals in the competition, scoring nine in 10 matches.
The legendary striker didn't score against his former club in the group phase, but five of his nine goals have come at home. Considering how explosive Barcelona is, I expect the 36-year-old to net his 10th of the competition.
📊 Barcelona vs. Borussia Dortmund odds
See the latest Champions League odds on all of today's other matchups.
🗓️ When is Barcelona vs. Borussia Dortmund?
📅 When: Wednesday, April 9🕗 Time: 3 p.m. ET📍 Location: Estadi Olimpic Lluis Companys (Barcelona)📺 How to watch: Paramount+, DZAN (Canada)🌡️ Weather: 59 degrees, 10% chance of precipitation, wind 7 mph ENE
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